hrp0097p1-45 | Diabetes and Insulin | ESPE2023

Common challenges of one uncommon syndrome - single center experience with Congenital Generalized Lipodystrophy

Slavcheva - Prodanova Olga , Archinkova Margarita , Yaneva Natasha , Modeva Iskra , Dimova Ivanka , Savova Radka

Aim: To present some therapeutic difficulties in patients with congenital generalized lipodystrophy (CGL) - a rare autosome recessive disorder characterized by complete absence of adipose tissue. For many years therapy was aimed only at metabolic consequences. In the past few years new pathophysiologic treatment has become available.Methods and materials: We present four girls – currently 25, 22, 16 and 15 years ol...